Research Associate

A Research Associate position is available within the Petter Brodin laboratory, Department of Immunology, and Inflammation, at Imperial College London. The post is funded by the Academy of Medical Sciences (AMS) and deals with experimental and computational analyses of individual immune cells in healthy children from birth to adolescence and from children with clinical signs of immune dysregulation.

In this Research Associate post, you will work on an exciting research project investigating the regulation and function of human immune systems in children of different ages and their relation to disease. We apply systems immunology methods to understand how the human immune system develops in relation to environmental factors early in life (Olin et al, Cell 2018 & Henrick et al, Cell 2021), and how its regulation and dysregulation can be discerned using advanced experimental and computational tools applied to blood samples from carefully phenotype patients.

We are seeking a candidate with strong immunological interest and knowledge and experience in both experimental and computational systems immunology. We expect you to be able to plan and perform in vitro cultures and stimulation experiments using human blood samples and perform flow cytometry and scRNA-sequencing experiments, as well as be able to perform at least basic computational analysis methods. You will be working with experienced experimentalists and data science experts in a collaborative way, so having a collaborative mindset and be interested in team science is key. We value careful documentation and meticulous experimental work, and we value creative individuals with innovative ideas.

To join our lab, you should be highly motivated and enthusiastic and should hold a PhD in immunology or other relevant disciplines. You will be joining a collaborative research environment with several other basic and translational immunology research groups. We expect that you will have strong organisational and communication skills, as well as the ability to work independently and as part of a team.

Duties and responsibilities

You should take initiative in the planning and execution of your research, including to identify and develop suitable techniques and analysis. You should always ensure the validity and reliability of your data, including good record-keeping. You should be willing and able to work both independently and as part of a team with a common goal. You should be prepared and capable of communicating your work, including in written reports and papers. Collegiality and maintaining a harmonious work environment are paramount.

Essential requirements

You should hold a PhD in Immunology or a related field. Previous experience with cellular immunology as well as technical know-how in Flow or Mass cytometry, and single-cell transcriptomic analysis is important. Good interpersonal skills are essential.

Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £38,194 - £41,388 per annum.

Further information

The position is funded by the Academy of Medical Sciences

Informal enquiries can be made to Petter Brodin (p.brodin@imperial.ac.uk)

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.

http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research/

Documents

• Research Associate - JD.pdf